TRansmural hEaliNg Definition in CroHn's Disease - The TRENCH1 Study

Status: Recruiting
Location: See all (18) locations...
Intervention Type: Procedure
Study Type: Observational
SUMMARY

Multicenter prospective cross-sectional study of CD patients, its aim is the construction of an objective and reproducible system for evaluation of Transmural healing in Crohn's Disease (CD). Primary objective : Objective definition of depth or grade of transmural healing in relation to radiologic signs observed during Magnetic Resonance Enterography (MRE) in CD

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 75
Healthy Volunteers: f
View:

• ≥ 18 years of age

• Patient diagnosed with CD for more than 6 months with histological confirmation available in his medical record.

• Indication for MRE based on routine clinical practice validated by the treating physician

• Any CD treatment will be authorized, such as biologicals (infliximab, adalimumab, vedolizumab, ustekinumab…), or immunomodulators (azathioprine, 6-mercaptopurine, methotrexate…).

• The subjects sign and date a written, informed consent form and any required privacy authorization prior to the initiation of the study.

• A subject can be enrolled into the study only if the grade of TH (assessed by the LRP) corresponding to the subject is not already fulfilled.

Locations
Other Locations
Belgium
CHU de Liège
NOT_YET_RECRUITING
Liège
France
CHU Amiens-Picardie (site Sud)
RECRUITING
Amiens
CHU de Bordeaux - Hôpital Haut-Lévêque
NOT_YET_RECRUITING
Bordeaux
APHP - Hôpital Ambroise Paré
NOT_YET_RECRUITING
Boulogne-billancourt
CHU de Clermont-Ferrand - Hôpital d'Estaing
RECRUITING
Clermont-ferrand
APHP - Hôpital Louis Mourier
NOT_YET_RECRUITING
Colombes
CHRU de Lille - Hôpital Claude Huriez
NOT_YET_RECRUITING
Lille
CHU Limoges Dupuytren
RECRUITING
Limoges
AP-HM - Hôpital Nord
NOT_YET_RECRUITING
Marseille
CHU de Montpellier - Hôpital Saint Eloi
RECRUITING
Montpellier
CHU de Nantes
NOT_YET_RECRUITING
Nantes
CHU de Nice - Hôpital l'Archet II
NOT_YET_RECRUITING
Nice
CHU de Nîmes - Hôpital Carémeau
NOT_YET_RECRUITING
Nîmes
APHP - Hôpital Européen Georges Pompidou (HEGP)
NOT_YET_RECRUITING
Paris
Hospices Civils de Lyon
NOT_YET_RECRUITING
Pierre-bénite
CHU Rennes - Hôpital Pontchaillou
NOT_YET_RECRUITING
Rennes
CHU de Saint Etienne - Hôpital Nord
NOT_YET_RECRUITING
Saint-priest-en-jarez
CHRU de Nancy - Hôpitaux de Brabois
NOT_YET_RECRUITING
Vandœuvre-lès-nancy
Contact Information
Primary
Sophie GEYL
sophie.geyl@chu-limoges.fr
+33 5 55 05 66 31
Backup
Laurent PEYRIN-BIROULET
peyrinbiroulet@gmail.com
+33 3 83 15 36 61
Time Frame
Start Date: 2023-09-28
Estimated Completion Date: 2025-08
Participants
Target number of participants: 210
Related Therapeutic Areas
Sponsors
Leads: Groupe d'Etude Therapeutique des Affections Inflammatoires Digestives

This content was sourced from clinicaltrials.gov