Prospective Observational Trial of Low-Dose Total Skin Electron Therapy in Mycosis Fungoides Using Rotisserie Technique

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Observational
SUMMARY

This clinical trial studies low- dose total skin electron therapy in treating patients with stage IB-IIIA mycosis fungoides that has not responded to previous treatment (refractory) or has returned after a period of improvement (relapsed). Radiation therapy uses high energy electrons to kill tumor cells and shrink tumors. Rotisserie technique is a method in which the patient receives total skin electron therapy while standing on a rotating platform. Giving low dose total skin electron therapy using rotisserie technique may kill tumor cells, while having fewer side effects, and may allow therapy to be repeated in future if clinically indicated.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Biopsy confirmed mycosis fungoides stage IB-IIIA

• Skin manifestations of mycosis fungoides that are refractory to or have relapsed on at least one prior therapy, which may include topical steroids

• Life expectancy \> 6 months

Locations
United States
Tennessee
Vanderbilt-Ingram Cancer Center
RECRUITING
Nashville
Contact Information
Primary
VICC Clinical Trials Information Program
800-811-8480
Time Frame
Start Date: 2016-05-22
Estimated Completion Date: 2026-09
Participants
Target number of participants: 60
Treatments
Quality of Life/ Grading Skin Findings
Patients' baseline quality of life is established by completion of an initial questionnaire, and skin lesion burden is quantified by physical examination using a recommended system . Following the standard of care radiation therapy, patients' completion of questionnaire, and physical examination is repeated for continued assessment.
Sponsors
Leads: Vanderbilt-Ingram Cancer Center
Collaborators: National Cancer Institute (NCI)

This content was sourced from clinicaltrials.gov