Serum Human Epididymis Protein 4 and Pulmonary Function Before and After Structural Quality Improvement Protocol Among Cystic Fibrosis Patients
Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY
To implement a quality improvement plan aimed at achieving a 5% increase in the Forced expiratory volume in 1st second (FEV1) (% predicted value) in cystic fibrosis (CF) patients with impaired pulmonary function parameters over 12 months. Additionally, the plan aims to measure serum human epididymis protein 4 (HE4) levels in the studied subjects before and after pulmonary function improvement.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 6
Healthy Volunteers: f
View:
• Pediatric CF patients diagnosed based on the Consensus Guidelines from the Cystic Fibrosis Foundation, with a positive sweat chloride test (≥60 milliequivalent/L) and/or the presence of two CF disease-causing gene mutations.
• Age ≥6 years.
• Forced expiratory volume in 1 second (FEV₁) ≤80%.
Locations
Other Locations
Egypt
Ain Shams university
RECRUITING
Cairo
Contact Information
Primary
Eman Fawzy, MD
eman199358@gmail.com
Egypt: 201011778583
Backup
Terez Boshra
Terezboshra@gmail.com
+201224035744
Time Frame
Start Date: 2024-10-07
Estimated Completion Date: 2025-12-12
Participants
Target number of participants: 35
Treatments
Pediatric CF patients aged 6 years and above with an FEV₁% predicted below 80%.
Using quality improvement principles for patient care and reassessing after one year.
Related Therapeutic Areas
Sponsors
Leads: Ain Shams University