Study to Enable New Diagnostics for Pulmonary Microbes in People With CF (SEND-CF)
Status: Recruiting
Location: See all (9) locations...
Study Type: Observational
SUMMARY
Sputum culture has been the best approach to detect harmful bacteria in the lungs of people with cystic fibrosis (CF). With the widespread use of new CF therapies (like Trikafta and Alyftrak), it is more difficult for people with CF to produce sputum even though they still have harmful bacteria in their lungs. The SEND-CF study is being done to see if there are other ways to detect harmful bacteria in the lungs.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 16
Healthy Volunteers: f
View:
• ≥ 16 years of age on day of study visit
• Documentation of CF Diagnosis
• Able to expectorate sputum
• Percent predicted FEV1 ≥ 30%
Locations
United States
California
University of California San Diego
NOT_YET_RECRUITING
La Jolla
Minnesota
The Minnesota Cystic Fibrosis Center
RECRUITING
Minneapolis
Missouri
Washington University School of Medicine
RECRUITING
St Louis
Nebraska
University of Nebraska Medical Center
NOT_YET_RECRUITING
Omaha
Ohio
Nationwide Children's Hospital
NOT_YET_RECRUITING
Columbus
Pennsylvania
University of Pennsylvania
RECRUITING
Philadelphia
University of Pittsburgh Medical Center
RECRUITING
Pittsburgh
Texas
University of Texas Southwestern
RECRUITING
Dallas
Wisconsin
Froedtert & Medical College of Wisconsin
RECRUITING
Milwaukee
Contact Information
Primary
Nikita Midamba
Nikita.midamba@seattlechildrens.org
206-884-0599
Backup
Anna Mead
Anna.mead@seattlechildrens.org
206-884-7531
Time Frame
Start Date: 2026-03-30
Estimated Completion Date: 2027-08-01
Participants
Target number of participants: 300
Related Therapeutic Areas
Sponsors
Collaborators: Cystic Fibrosis Foundation, University of Pennsylvania
Leads: Chris Goss