Personalized Therapy of Cystic Fibrosis: Set-up of Response Markers
Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The purpose of this study is to determine which biological marker, or association of biological markers, best predict clinical response of cystic fibrosis patients to CFTR modulators.
Eligibility
Participation Requirements
Sex: All
Healthy Volunteers: f
View:
• Cystic fibrosis patients treated by CFTR modulators (Ivacaftor or the association Ivacaftor-Lumacaftor)
• Cystic fibrosis patients non treated by CFTR modulators
• Patients in whom cystic fibrosis diagnosis has been suspected, but excluded by physiological and genetic investigations
Locations
Other Locations
France
Necker Hospital
RECRUITING
Paris
Contact Information
Primary
Isabelle Sermet, MD, PhD
isabelle.sermet@aphp.fr
33 1 44 49 48 87
Backup
Jean-Louis Pérignon, MD, PhD
jean-louis.perignon@aphp.fr
Time Frame
Start Date: 2016-05
Estimated Completion Date: 2026-10
Participants
Target number of participants: 75
Treatments
Other: Cystic fibrosis, treated
Cystic fibrosis patients treated either by Ivacaftor or by the association Ivacaftor-Lumacaftor
Other: Cystic fibrosis, non treated
Cystic fibrosis patients, non treated by a CFTR modulator
Other: Non-Cystic fibrosis
Patients in whom cystic fibrosis diagnosis has been suspected, but excluded by physiological and genetic investigations
Related Therapeutic Areas
Sponsors
Leads: Hôpital Necker-Enfants Malades
Collaborators: Vaincre la Mucoviscidose, Association Mucoviscidose-ABCF2