Music Therapy for Autobiographical Memory and Neuropsychiatric Symptoms in Alzheimer Disease

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This study is designed to assess the feasibility that individualized reminiscence-based virtual music therapy sessions can enhance autobiographical memory, mood, and cognition in patients with mild cognitive impairment (MCI) or mild dementia due to Alzheimer's Disease (AD). 60 patients with MCI or mild dementia due to AD will receive two 30 minutes reminiscence-targeted virtual music therapy interventions per week for 8 weeks (a total of 16 sessions). Participants' (or supported by the study partner) self-reported and measurable outcomes including cognitive, anxiety, quality of life, and autobiographical memory will be assessed before and after the 8-week course of treatment. Blood-oxygenation level-dependent (BOLD) in functional magnetic resonance imaging (fMRI) will also be also measured before and after the 8-week course of treatment.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 89
Healthy Volunteers: f
View:

• Age 18-89

• Mild Cognitive Impairment (MoCA score: 18-25) or Early AD (MoCA score: 17-24)

Locations
United States
Maryland
Johns Hopkins School of Medicine
RECRUITING
Baltimore
Contact Information
Primary
Alexander Pantelyat, MD
apantel1@jhmi.edu
4105023290
Backup
Kyurim Kang, PhD
kkang19@jhmi.edu
4437422223
Time Frame
Start Date: 2022-07-18
Estimated Completion Date: 2026-04
Participants
Target number of participants: 60
Treatments
Experimental: Virtual Music Therapy
Participants will attend two 30 minutes long virtual music therapy sessions per week for 8 weeks using Zoom.
Related Therapeutic Areas
Sponsors
Leads: Johns Hopkins University

This content was sourced from clinicaltrials.gov