Shanghai Non-pharmacological Intervention for Mild Cognitive Impairment and Mild Alzheimer's Disease: Combined Low Inflammatory-index Diet, Physical Exercises, and Cognitive Training in Nursing Home

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This study is a multicentre, randomized, double-blind, controlled trial that aims to investigate the efficacy of multi-domain life-style intervention including low inflammatory-index diet, exercise, and cognitive training in patients with mild cognitive impairment and mild Alzheimer's disease.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 60
Maximum Age: 90
Healthy Volunteers: f
View:

• Aged 60-90 years

• In accordance with the diagnostic criteria for mild cognitive impairment due to Alzheimer's disease or mild Alzheimer's disease from the National Institutes of Health National Institute on Aging-Alzheimer's Association (NIA-AA) (2011)

• The Hamilton depression rating scale/17 edition (HAMD) total score≤10

• Neurological examination: no obvious signs

• Education: primary school (grade 6) or above and capacity to complete tests for cognitive ability

• Capacity to give consent

Locations
Other Locations
China
Ruijin Hospital affiliated to Shanghai Jiaotong University School of Medicine
RECRUITING
Shanghai
Contact Information
Primary
Binyin Li, Dr
lby11917@rjh.com.cn
021-64370045
Time Frame
Start Date: 2023-05-11
Estimated Completion Date: 2026-08-30
Participants
Target number of participants: 180
Treatments
Experimental: Multi-domain intervention group
Patients in this arm will receive multi-domain life-style intervention including low inflammatory-index diet, exercise, and cognitive training.
Experimental: Exercise and cognitive training
Patients in this arm will receive the intervention of exercise and cognitive training.
No_intervention: Standard health counseling at baseline
Patients in this arm will have their habitual diet and life style. No particular intervention or consultation would be provided.
Related Therapeutic Areas
Dementia
Alzheimer's Disease
Sponsors
Leads: Ruijin Hospital
Collaborators: Shanghai Sinopharm Nursing Care Center

This content was sourced from clinicaltrials.gov

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