A Multi-domain Lifestyle Intervention Among Aged Community-residents in Zhejiang, China

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

A study conducted in Finland discovered that a multidomain intervention, consisting of physical activity, nutritional guidance, cognitive training, social activities, and management of vascular risk factors, effectively decelerated cognitive decline in healthy older adults who were at an increased risk of cognitive decline. The HERITAGE study is a 2-year clustered randomized controlled trial (clustered-RCT) that explores the efficacy of a multidomain intervention among 1200 elderly residents with a higher risk of cognitive decline and dementia in Zhejiang Province, China

Eligibility
Participation Requirements
Sex: All
Minimum Age: 60
Maximum Age: 80
Healthy Volunteers: t
View:

• At risk of cognitive decline: cognitive performance at the mean level or slightly lower than expected for age with no dementia (AD8\>=3 and/or 5-min MoCA \>, \< 11)

• Free of physical disabilities that preclude participation in the study

• Willing to complete all study-related activities for 24 months

• Willing to be randomized to either lifestyle intervention group

Locations
Other Locations
China
School of Public Health and The Second Affiliated Hospital of School of Medicine, Zhejiang University, Hangzhou, China
RECRUITING
Hangzhou
Contact Information
Primary
Xin Xu, PhD
xuxinsummer@zju.edu.cn
+8613575760802
Backup
Changzheng Yuan, PhD
chy478@zju.edu.cn
Time Frame
Start Date: 2023-05-28
Estimated Completion Date: 2027-04-28
Participants
Target number of participants: 1200
Treatments
Experimental: Structured Multi-domain Intervention
Multi-domain structured intervention will be tailored by Chinese traditional and social norms and then conducted among the intervention group. That includes: Nutritional and dietary instruction, Cognitive training, Physical exercises, and Vascular risks monitoring and control.
Experimental: Self-Guided Intervention
Every 6-12 months, control group will receive a regular health education campaign to encourage a healthy lifestyle and a regular health monitoring and examination of blood pressure, weight, fasting blood glucose and liposome group
Related Therapeutic Areas
Sponsors
Leads: Zhejiang University

This content was sourced from clinicaltrials.gov