Investigations of Dementia in Parkinson Disease
Status: Recruiting
Location: See location...
Intervention Type: Radiation
Study Type: Observational
SUMMARY
The purpose of this study is to use a brain imaging method called Pittsburgh B (PIB) Positron Emission Tomography (PET) and Vesicular Cholinergic Transport (VAT) PET to determine dementia subtypes in patients with Parkinson disease (PD). The ultimate goal of this project is to be able to identify individuals with PD who are at risk of developing dementia, and to distinguish the underlying cause of dementia.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 50
Healthy Volunteers: t
View:
• PD patients must exhibit three of the following cardinal signs: rest tremor, rigidity, bradykinesia, or postural instability; or two of these features with one of the first three displaying asymmetry.
Locations
United States
Missouri
Washington University in St. Louis
RECRUITING
St Louis
Contact Information
Primary
Andrea Slavik, RN, BSN
andreaslavik@wustl.edu
314 273 8313
Backup
Susan Donovan
donovan@wustl.edu
314 362 6026
Time Frame
Start Date: 2016-06
Estimated Completion Date: 2030-03
Participants
Target number of participants: 320
Treatments
Parkinsons Disease
Individuals with Parkinsons Disease
Healthy Controls
Individuals without Parkinsons Disease
Related Therapeutic Areas
Sponsors
Leads: Washington University School of Medicine
Collaborators: National Institute on Aging (NIA), National Institutes of Health (NIH), National Institute of Neurological Disorders and Stroke (NINDS)