AvoCog - The Effect of Daily Avocado Intake on Cognitive Function in Older Adults

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this clinical trial is to determine if adding avocados to the diet of impacts cognition in 70 older adults, age 65-85, without dementia. We will test for change in functional MRI, cognitive performance, and brain blood flow. Intervention group participants will be asked to consume 1 avocado per day for 12 weeks. Participants in the control group will be asked to continue their normal intake for 12 weeks. Throughout the study, participants will be asked to perform cognitive tests, MRI, blood tests, and questionnaires.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 65
Maximum Age: 85
Healthy Volunteers: t
View:

• Males and females aged 65-85 years

• Good general health with no concomitant disease

• BMI 18.5 - 35 kg/m2

• Mini Mental State Exam ≥26

• Reports consuming ≤2 medium avocados per month

• Reports consuming ≤3 servings of carotenoid-rich foods per week and ≤3 servings of fruits and vegetables per day

• Skin carotenoid content \<400

Locations
United States
Kansas
University of Kansas Medical Center
RECRUITING
Kansas City
Contact Information
Primary
Emma Kelly, MS
ekelly9@kumc.edu
913-588-7683
Backup
Matthew Taylor, PhD
mtaylor3@kumc.edu
913-588-5363
Time Frame
Start Date: 2024-04-09
Estimated Completion Date: 2025-12
Participants
Target number of participants: 70
Treatments
Experimental: Avocado Group
Participants will consume 1 avocado per day and receive education to maintain usual caloric intake for 12 weeks and participate in 4 study visits.
No_intervention: No Diet Modification Group
Participants will continue their normal dietary pattern for 12 weeks and participate in 4 study visits.
Related Therapeutic Areas
Sponsors
Collaborators: Avocado Nutrition Center
Leads: University of Kansas Medical Center

This content was sourced from clinicaltrials.gov