Effects of Different Resistance Training Volumes on Cognitive Function, Oxidative Stress, Immunological Response, Lipid Profile, Glycemic Status, Liver Function, Muscle Function, Hemodynamic Response, and Physical Performance in Individuals With Mild Cognitive Impairment

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This research project aims to analyze the effects of different resistance training volumes on cognitive function, oxidative stress, immunological response, lipid profile, glycemic status, liver function, muscle function, hemodynamic response, and physical performance in individuals with mild cognitive impairment. First the investigators will analyze the effects of a single resistance training session (acute effects) with one and three sets on hemodynamic and physical performance in individuals with mild cognitive impairment. After, the investigators will analyze the effects of an 8-week resistance training program with one or three sets on cognitive function, oxidative stress, immunological response, lipid profile, glycemic status, liver function, muscle function, hemodynamic response, and physical performance in individuals with mild cognitive impairment. The investigators hypothesize that a single resistance training session of one or three sets will increase the acute hemodynamic and physical performance stress in individuals with mild cognitive impairment, although with a higher magnitude in the session with three sets. Furthermore, we hypothesize that eight weeks of resistance training with one or three sets will induce similar improvements in cognitive function, oxidative stress, immunological response, lipid profile, glycemic status, liver function, muscle function, hemodynamic response, and physical performance in individuals with mild cognitive impairment.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 50
Healthy Volunteers: t
View:

• Clinical diagnosis of mild cognitive impairment

• SPPB score ≥ 3 points

• Willingness to participate in the interventions and collaborate with the research team

• Must be able to provide informed consent (oral or written)

Locations
Other Locations
Portugal
University of Beira Interior
RECRUITING
Covilha
Contact Information
Primary
Nuno Fonseca, Master's
nuno1977fonseca@gmail.com
918241354
Time Frame
Start Date: 2023-12-01
Estimated Completion Date: 2024-12-31
Participants
Target number of participants: 80
Treatments
Experimental: One Resistance Training Set (Single Session)
The participants will perform one resistance training session with one set.
Experimental: Three Resistance Training Sets (Single Session)
The participants will perform one resistance training session with three sets.
Experimental: One Resistance Training Set (8 Weeks)
The participants will perform eight weeks of resistance training (two sessions per week, separated by 72 hours of rest) with one set.
Experimental: Three Resistance Training Sets (8 Weeks)
The participants will perform eight weeks of resistance training (two sessions per week, separated by 72 hours of rest) with three sets.
Experimental: Control (8 Weeks)
The participants will not perform any form of physical exercise during the intervention period of eight weeks.
Related Therapeutic Areas
Sponsors
Leads: University of Beira Interior
Collaborators: Research Center in Sports Sciences, Health Sciences and Human Development

This content was sourced from clinicaltrials.gov