Impact of the Digital Multi-domain Cognitive Intervention in High-risk Populations for Dementia

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Dementia is a chronic, progressive neurodegenerative disease characterized by acquired cognitive impairment as its core manifestation. The most common type of dementia is Alzheimer's Disease (AD), also known as Senile Dementia, accounting for 60-80% of all dementia cases. Currently, there are approximately 10 million AD patients in China, with the number showing an increasing trend year by year, imposing a heavy economic and caregiving burden on families and society. Studies have shown that AD has a clinically silent period of 15 to 20 years (SCD\MCI), where the risk of developing dementia is ten times higher than that of healthy elderly individuals. Nearly 50% of MCI patients progress to dementia within 5 years, and about 14.1% of SCD patients develop dementia within the same timeframe. Early detection, diagnosis, and intervention are currently the most effective strategies for preventing and treating AD. Therefore, this study aims to verify the intervention effect of integrated cognitive intervention in high-risk populations for senile dementia (SCD, MCI) based on the cognitive rehabilitation model through randomized controlled trials, and to analyze attrition rates, participation rates, etc., which have good research and application value.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 55
Healthy Volunteers: f
View:

• MCI (refer to Peterson's diagnostic criteria) or SCD (refer to the diagnostic framework proposed by Jak bondi and Jessen et al.);

• Able to communicate normally in Mandarin;

• Certain level of comprehension and judgment abilities, aware of the purpose of the survey and consents to participate.

Locations
Other Locations
China
Fujian Provincial Hospital
RECRUITING
Fuzhou
Contact Information
Primary
lian fayang, MD
fjslkyk@163.com
0591-87557768
Backup
Yuanjiao Yan, PhD
yuanjiao1994@126.com
18120826271
Time Frame
Start Date: 2024-06-04
Estimated Completion Date: 2026-12-31
Participants
Target number of participants: 128
Treatments
Experimental: Intervention group
Participants in the intervention group received the digtal multi-domain cognitive intervention. The digital multi-domain cognitive intervention system is used to carry out various intervention activities. The activities include learning about health knowledge once a week; home-based exercise three times per week, for 30 minutes each time; art therapy once a week, for 90 minutes at a time; and cognitive training, which includes memory, attention, executive function, and visuospatial training, conducted three times per week, with each session lasting 30 minutes.
Other: Control group
Participant in the control group reveived the health education , once a week, covering the prevention and treatment of chronic diseases in the elderly, as well as healthy lifestyles for the elderly
Related Therapeutic Areas
Sponsors
Leads: Fujian Provincial Hospital

This content was sourced from clinicaltrials.gov