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Healthy Taiwan Cultivation Plan: Building an Active-ageing Lifestyle in Rural Taiwan Through Integrating Novel Healthcare Technology - From Mitigating Digital and Health Literacy Gap, Establishing a Mobile Interactive Pro-active-ageing Information Platform, to Exploring Multi-dimensional Digital Biomarkers of Ageing

Status: Recruiting
Location: See location...
Intervention Type: Device, Behavioral, Biological
Study Type: Observational
SUMMARY

Taiwan is entering a super-aged society in 2025, with more than 20% of the population aged 65 years or older. This rapid demographic shift, combined with increasing rates of chronic diseases, frailty, and dementia, has created growing challenges for healthcare and caregiving systems. Yunlin County, particularly its coastal region, has been one of Taiwan's earliest super-aged areas, showing higher rates of diabetes (10.5%), hypertension (28%), hyperlipidemia (26%), dementia (8%), and depression (12%) compared with national averages. Lifestyle factors such as tobacco (30%), betel nut (8%), and alcohol (15%) use are also more prevalent among local residents. From 2022 to 2024, health screenings at CMU Beigang Hospital revealed a 36.1% abnormality rate among 12,222 visits, while another 5,965 assessments from the county's ICOPE program showed similarly high rates. Many older adults, particularly retired agricultural and fishing workers, experience sedentary lifestyles and polypharmacy-related risks, which worsen frailty, insomnia, depression, and cognitive decline. Low general and digital health literacy further limits their ability to adopt preventive behaviors, forming a vicious cycle between poor health and aging. To address these challenges, the Ministry of Health and Welfare launched the Healthy Taiwan Cultivation Plan. In alignment with this initiative, this project-led by CMU Beigang Hospital in collaboration with the National Health Research Institutes-aims to develop a wearable- and mobile-based health promotion model for rural older adults. The study will integrate research-grade actigraphy (Geneactiv), a mobile health platform (iMED), and the in-bed sensor iCue to monitor behavior, promote active aging, and enhance health and digital literacy. Ultimately, this project seeks to establish Taiwan's first integrated digital aging database and identify digital biomarkers for predicting cognitive and functional decline in older adults.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 60
Healthy Volunteers: t
View:

• Currently living or receiving care in a stable environment for at least four weeks prior to enrollment:

‣ For community-based participants: must have resided at the same address for ≥4 weeks.

⁃ For day-care participants: must have attended activities at the same dementia or elderly day-care center for ≥4 weeks.

• Able and willing to participate in the study procedures.

• Informed consent must be obtained before participation.

‣ If the participant's cognitive function has declined to a level that prevents self-consent, written consent will be obtained from a legally authorized representative or primary caregiver.

Locations
Other Locations
United Kingdom
China Medical University Beigang Hospital
RECRUITING
London
Contact Information
Primary
Dr Ta-Wei Guu Consultant psychiatrist, MD, PhD
066753@tool.caaumed.org.tw
+886-57837901
Backup
Yueh-Heng Chiang, RN, MS.
isyuehheng@gmail.com
Time Frame
Start Date: 2026-04-22
Estimated Completion Date: 2029-12-31
Participants
Target number of participants: 140
Treatments
Health Promotion through Wearable and Mobile Technology
Participants will join a community-based health program integrating wearables, mobile health platforms, and structured education to promote active lifestyles, enhance health literacy, and collect longitudinal data in older adults in rural Taiwan.~Participants will:~1. Wear a research-grade wrist actigraphy device (GeneActiv) to record activity, sleep, and light exposure for ≥2 weeks.~2. Use the iMED mobile app (NHRI, Taiwan) for feedback, health education, and medication tracking.~3. For participants with limited mobility, use an under-mattress iCue sensor to monitor respiration and movement.~4. Attend Aging Well Taiwan sessions based on the WHO ICOPE framework.~5. Provide baseline and follow-up blood samples for dementia-related biomarkers (Tau, Aβ, NfL) and APOE genotyping.
Related Therapeutic Areas
Sponsors
Collaborators: Ministry of Health and Welfare, Taiwan
Leads: China Medical University Hospital

This content was sourced from clinicaltrials.gov