Personalized Memory Enhancement in Aging: Pattern-Optimized tACS With Closed-Loop Precision Modulation
Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This project optimizes high-resolution transcranial Alternating Current Stimulation (tACS) to improve memory in healthy older adults, advancing drug-free approaches for Alzheimer's disease and related dementia (ADRD). We test stimulation schedules and develop an adaptive, brain-guided tACS system to strengthen memory-supporting networks.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 65
Healthy Volunteers: t
View:
• 65 years of age or older
• normal or corrected-to-normal vision
• color vision
Locations
United States
Massachusetts
111 Cummington Mall
RECRUITING
Boston
Contact Information
Primary
Robert Reinhart, PhD
rmgr@bu.edu
(617) 353-9481
Time Frame
Start Date: 2026-06-01
Estimated Completion Date: 2031-01-31
Participants
Target number of participants: 240
Treatments
Experimental: 1-day patterned tACS
Experimental: 3-day patterned tACS
Experimental: 5-day patterned tACS
Experimental: 1-day continuous tACS
Experimental: 3-day continuous tACS
Experimental: 5-day continuous tACS
Related Therapeutic Areas
Sponsors
Leads: Boston University Charles River Campus