An Annual Dosing Study of Donanemab in Participants Who Completed Donanemab Study AACM
Status: Recruiting
Location: See all (59) locations...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 3
SUMMARY
The main purpose of this study is to determine if participants who previously took donanemab get clinical benefit when they receive annual doses. For each participant, the study will last up to 2.5 years and will include 6 visits.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 55
Healthy Volunteers: f
View:
• Have completed study AACM Addendum 7.
• Have a reliable study partner and backup study partner familiar with overall function and behavior, such as day-to-day activities and cognitive abilities.
• Are individuals assigned female at birth who are not of childbearing potential, or are individuals assigned male at birth.
• Contraceptive use by participants should be consistent with local regulations regarding the methods of contraception for those participating in clinical studies.
Locations
United States
Arizona
Banner Alzheimer's Institute
NOT_YET_RECRUITING
Phoenix
California
Care Access - Huntington Beach
RECRUITING
Huntington Beach
Irvine Clinical Research
RECRUITING
Irvine
Healthy Brain Clinic
RECRUITING
Long Beach
Artemis Institute for Clinical Research
RECRUITING
Riverside
Clinical Trials Research
RECRUITING
Sacramento
Artemis Institute for Clinical Research
NOT_YET_RECRUITING
San Diego
Syrentis Clinical Research
RECRUITING
Santa Ana
Providence Medical Foundation
RECRUITING
Santa Rosa
Infectious Disease Doctors Medical Group, APC
RECRUITING
Walnut Creek
Florida
VIN - Aventura
RECRUITING
Aventura
Bradenton Research Center, Inc.
RECRUITING
Bradenton
Finlay Medical Research
RECRUITING
Greenacres City
Jacksonville Center for Clinical Research
RECRUITING
Jacksonville
K2 Medical Research ORLANDO
RECRUITING
Maitland
Merritt Island Medical Research, LLC
RECRUITING
Merritt Island
Finlay Medical Research
RECRUITING
Miami
VIN-Andrew Lerman
RECRUITING
Miami
Indago Research & Health Center, Inc
RECRUITING
Miami Lakes
Adult Medicine of Lake County, Inc.
RECRUITING
Mt. Dora
Suncoast Clinical Research, Inc.
RECRUITING
New Port Richey
Charter Research - Orlando
RECRUITING
Orlando
Headlands Research Orlando
RECRUITING
Orlando
Emerald Coast Neurology - Airport Boulevard
RECRUITING
Pensacola
Progressive Medical Research
RECRUITING
Port Orange
Care Access - Tampa
RECRUITING
Tampa
K2 Medical Research - Tampa
NOT_YET_RECRUITING
Tampa
Charter Research - The Villages
RECRUITING
The Villages
Conquest Research
RECRUITING
Winter Park
Georgia
Center for Advanced Research & Education
RECRUITING
Gainesville
North Georgia Clinical Research
RECRUITING
Woodstock
Iowa
Covenant Medical Center
NOT_YET_RECRUITING
Waterloo
Idaho
Northwest Clinical Trials
RECRUITING
Boise
Illinois
Great Lakes Clinical Trials - Andersonville
RECRUITING
Chicago
Indiana
Care Access - South Indianapolis
RECRUITING
Indianapolis
Josephson Wallack Munshower Neurology, PC
RECRUITING
Indianapolis
Louisiana
Care Access - Lake Charles (Bayou Pines)
RECRUITING
Lake Charles
Massachusetts
Boston Center for Memory
RECRUITING
Newton
MedVadis Research Corporation
NOT_YET_RECRUITING
Waltham
Michigan
Revival Research Institute, LLC
NOT_YET_RECRUITING
Southfield
Missouri
Citizens Memorial Hospital District
RECRUITING
Bolivar
North Carolina
Monroe Biomedical Research
NOT_YET_RECRUITING
Monroe
New Jersey
The Cognitive and Research Center of New Jersey
RECRUITING
Springfield
Nevada
Vector Clinical Trials
RECRUITING
Las Vegas
Ohio
NDx Clinical Research, Inc.
NOT_YET_RECRUITING
Dayton
Care Access - Lima
RECRUITING
Lima
Texas
Senior Adults Specialty Research
NOT_YET_RECRUITING
Austin
Gadolin Research
RECRUITING
Beaumont
The University of Texas Health Science Center at Houston
RECRUITING
Houston
Consano Clinical Research, LLC
NOT_YET_RECRUITING
Shavano Park
Washington
Northwest Clinical Research Center
RECRUITING
Bellevue
Universal Research Group
RECRUITING
Tacoma
Other Locations
Japan
Tokyo-Eki Center-building Clinic
NOT_YET_RECRUITING
Chūōku
P-One Clinic
NOT_YET_RECRUITING
Hachiōji
National Center for Geriatrics and Gerontology
NOT_YET_RECRUITING
Ōbu
Samoncho Clinic
NOT_YET_RECRUITING
Shinjuku
Yotsuya Internal Medicine Clinic
NOT_YET_RECRUITING
Shinjyuku
Tokyo Metropolitan Institute for Geriatrics and Gerontology
NOT_YET_RECRUITING
Tabashi City
Puerto Rico
SCB Research Center
NOT_YET_RECRUITING
Bayamón
Contact Information
Primary
Trial questions or participation questions: 1-877-CTLILLY (1-877-285-4559) or
LillyTrials@Lilly.com
1-317-615-4559
Backup
Physicians interested in becoming principal investigators please contact
clinical_inquiry_hub@lilly.com
Time Frame
Start Date: 2026-05-22
Estimated Completion Date: 2029-09
Participants
Target number of participants: 550
Treatments
Experimental: Donanemab
Donanemab administered intravenously (IV)
Placebo_comparator: Placebo
Placebo IV
Related Therapeutic Areas
Sponsors
Leads: Eli Lilly and Company