Efficacy of Dengue Infection With Warning Signs Treated With Dexamethasone
Status: Recruiting
Location: See all (2) locations...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The goal of this randomized double-blinded placebo-controlled trial is to learn about dexamethasone and the treatment of severe dengue population. The main question it aims to answer are steroid therapy may be effective in dengue.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 7
Maximum Age: 99
Healthy Volunteers: f
View:
• Laboratory confirmed Dengue infected patients (Positive NS1 Ag or anti-DENV IgM by Dengue Duo test)
• And still in febrile phase (Body temp\>37.5 C)
• Shock : Sys\<90mmHg or Narrow PP (\<20mmHg) orTachycardia (pulse\>100/min) with Hematocrit decreased ≥20 %
• Fluid accumulation and respiratory distress
• Severe bleeding
• Severe organ involvement
Locations
Other Locations
Thailand
Chulalongkorn University
RECRUITING
Bangkok
King Chulalongkorn Memorial Hospital
RECRUITING
Bangkok
Time Frame
Start Date: 2022-10-16
Estimated Completion Date: 2027-12-31
Participants
Target number of participants: 200
Treatments
Placebo_comparator: Placebo
Experimental: Intervention
Related Therapeutic Areas
Sponsors
Leads: Chulalongkorn University