Impact of the New Generation Anti-diabetic Drugs on Diabetic Retinopathy

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

This study aims to test the impact of new-generation anti-diabetic drugs, such as SGLT2 inhibitors and DPP-4 inhibitors, on the development of diabetic retinopathy (DR). The study hypothesizes that these drugs have protective effects in diabetic retinopathy by delaying its incidence compared to older agents (including metformin) only. Early intervention is critical, as treatment options for advanced stages of DR are limited in terms of their ability to restore impaired vision and their high associated costs. By focusing on delaying the occurrence of diabetic retinopathy, the investigators aim to reduce the burden of DR and improve the quality of life for diabetic patients.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 25
Healthy Volunteers: f
View:

• Diagnosed with Type 2 Diabetes for \>5 years

• Using Diabetes medications (metformin, sulfonylureas, SGLT2 inhibitors, DPP-4 inhibitors) for a period of 2-3 years

Locations
Other Locations
Egypt
Alexandria University Main Hospitals - Diabetes clinics/ Ophthalmology clinics
RECRUITING
Alexandria
Contact Information
Primary
Sara A Belal
phar-sara.belal@alexu.edu.eg
+201554630615
Time Frame
Start Date: 2025-08-01
Estimated Completion Date: 2026-09
Participants
Target number of participants: 70
Treatments
Classical Oral Anti-Diabetic Drugs
New-generation Oral Antidiabetic Drugs
Sponsors
Leads: Sara A Belal

This content was sourced from clinicaltrials.gov