• Adults (≥18 years) with type 1 diabetes

• Diabetes duration of ≥5 years

• Persistent urine albumin-to-creatinine ratio (UACR) ≥ 30 mg/g, on the most recent two measurements within the prior 3 years

• Estimated glomerular filtration rate ≥ 30 mL/min/1.73m2

• Stable doses of drugs altering blood pressure (e.g., Angiotensin-converting enzyme inhibitor) required for at least 4 weeks prior to randomization, and requested for the duration of the trial

• Stable doses of lipid-lowering medications required for at least 4 weeks prior to randomization, and requested for the duration of the trial

• Adequate contraceptive method for females of child-bearing potential