REducing SPEECH-related Side-effects of Deep Brain Stimulation in Parkinson's Disease Via Automated Speech Analysis
The investigators' objective is to improve L-dopa sensitive PD-related dysarthria and at the same time reduce DBS-induced speech disorders with the help of automated acoustic analysis in patients with STN-DBS-induced dysarthria.
• Idiopathic Parkinson-Syndrome according to the Movement Disorders Society Criteria
• Treatment with bilateral deep brain stimulation in the subthalamic nucleus (for parts 1, 2 and 3)
• Time since DBS-STN operation ≥ 3 month (for parts 1, 2 and 3)
• Able to give informed consent as documented by signature
• Fluent in Swiss-German or German
• STN-DBS-induced dysarthria. In an operational definition, all PD-patients who reported -worsening of speech time-locked to STN-DBS implantation or patients with dysarthria on chronic stimulation improving with reduction of stimulation amplitudes in the context of postoperative routine follow up will be defined as having STN-DBS-induced dysarthria