Pseudoephedrine Prophylaxis for Prevention of Middle Ear Barotrauma in Hyperbaric Oxygen Therapy
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The purpose of this research is to study whether the use of pseudoephedrine can help prevent middle ear trauma during HBOT. Pseudoephedrine is an approved drug that is used for temporary relief of nasal or sinus pain and pressure.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• New patient requiring HBOT (either inpatient or outpatient)
• Age greater than or equal to 18 years and less than 80 years
• Fluent in English
• Full decision capacity
• Able and medically cleared to swallow a pill
Locations
United States
California
John Muir Health
RECRUITING
Walnut Creek
Contact Information
Primary
Jacinta Showers, RN
jacinta.showers@johnmuirhealth.com
9259473212
Backup
Todd Kessinger, MD, MD
todd.kessinger_MD@johnmuirhealth.com
9259473212
Time Frame
Start Date: 2023-01-31
Estimated Completion Date: 2026-07
Participants
Target number of participants: 90
Treatments
Experimental: Pseudoephedrine
over the counter pseudoephedrine
Placebo_comparator: Placebo
pharmacy created placebo capsule
Related Therapeutic Areas
Sponsors
Leads: John Muir Health