Ultrasound Evaluation of Diaphragmatic Functions and Parasternal Intercostal Muscle Thickening Fraction as Predictors of Successful Weaning From Mechanical Ventilation.
Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY
Critically ill patients frequently develop respiratory muscle dysfunction that may contribute to difficult and prolonged weaning from mechanical ventilation. that is besides complications such as barotrauma, ventilator-acquired pneumonia, accumulation of secretions, and lung atelectasis. The ultrasound estimation of parasternal intercostal muscle and diaphragmatic functions is a method to evaluate if there is a good chance of weaning outcomes.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• 1\. Adult patients more than 18 years old. 2. Patient on mechanical ventilation more than 48 hours.
Locations
Other Locations
Egypt
Ain shams university hospitals
RECRUITING
Cairo
Contact Information
Primary
Mohamed I Ezz eldein
mohamedislam@med.asu.edu.eg
+2-1148394581
Time Frame
Start Date: 2026-01-01
Estimated Completion Date: 2026-08-01
Participants
Target number of participants: 77
Treatments
diaphragmatic and parasternal muscles function assessment
Patients who fulfilling the initial parameters for possibility of weaning will undergo spontaneous breathing trial (SBT) for 30 minutes.~All patients will be positioned in a semi sitting position at approximately 30 degree, and will be monitored closely during SBT period.~Ultrasound assessment for the parasternal intercostal and diaphragmatic muscle functions will be done at the end of SBTs for all patients.~Ultrasound assessment of diaphragm:~Diaphragmatic excursion; The diaphragmatic movement will be measured using a 3.5-MHz ultrasound probe. With the probe fixed on the chest wall during respiration, the patient will be asked to take a maximum breath. The right hemi-diaphragm will be measured by positioning the probe between the mid-clavicular and mid-axillary lines below the right costal margin (subcostal approach) using the liver as acoustic window. The probe will be positioned medially, cephalic and dorsally. Till the hemi-diaphragm will be well visualized. The M-mood will be ap
Related Therapeutic Areas
Sponsors
Leads: Ain Shams University