Local Versus Systemic Methotrexate in Management of Uterine Ectopic Pregnancy: A Randomized Trial
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This study aims to compare local and systemic methotrexate in the management of uterine ectopic pregnancy regarding the duration of beta human chorionic gonadotropin (hCG) clearance and need for further management options.
Eligibility
Participation Requirements
Sex: Female
Minimum Age: 20
Maximum Age: 40
Healthy Volunteers: f
View:
• Age from 20 to 40 years.
• Women with uterine ectopic pregnancy (interstitial pregnancy, cervical pregnancy, or cesarean scar pregnancy).
• Gestational age is less than 9 weeks, the embryo size is smaller than 10 mm, and the serum beta-human chorionic gonadotropin (β-hCG) levels are less than 10,000 mIU/mL.
Locations
Other Locations
Egypt
Tanta University
RECRUITING
Tanta
Contact Information
Primary
Mai N Ageez, MD
mai.ageez@med.tanta.edu.eg
00201062388870
Time Frame
Start Date: 2024-08-15
Estimated Completion Date: 2025-07-01
Participants
Target number of participants: 34
Treatments
Experimental: Systemic Methotrexate
Patients will receive systemic methotrexate (intramuscular; 50 mg/m2 body weight).
Experimental: Local Methotrexate
Patients will receive local methotrexate (25 mg methotrexate as a fixed dose).
Related Therapeutic Areas
Sponsors
Leads: Tanta University