Social Interventions for Support During Treatment for Endometrial Cancer and Recurrence
The SISTER study is a randomized trial, looking at various modalities of social support for Black patients undergoing treatment for endometrial cancer. There are three study arms: group support, 1:1 peer support, and enhanced usual care. The primary outcome is treatment completion, and the secondary outcome is social isolation.
• Adult 18 years of age or older; and
• Self-identify as Black/African American
• Presenting with high-risk EC established by anatomic pathology as tumor stage and grade classification by the following:
‣ Pathology documentation from any hospital/clinic/medical center, and
⁃ FIGO Stage 1A with Grade 2, Grade 3, or Grade 4 of any histology type or
⁃ FIGO Stage 1A with non-endometrioid (carcinosarcoma, serous, clear cell, undifferentiated or mixed) histology
⁃ FIGO Stage 1B, 2, 3, or 4 of any grade or histology
⁃ Recurrent endometrial cancer of any stage or grade
• Documented provider recommendation and patient plan to initiate adjuvant therapy with chemotherapy, radiation, and/or immunotherapy.