Exercise as a Preventive Agent to Combat Immobility in Patients With Ovarian or Endometrial Cancers Receiving Chemotherapy
The purpose of this research is to determine whether a 16-week virtually supervised aerobic and resistance exercise program is feasible in patients receiving first-line chemotherapy after surgery for ovarian or endometrial cancer and if it will improve lower extremity function (function of the legs), lessen chemotherapy-induced peripheral neuropathy (CIPN; numbness or tingling in the hands or feet), and if there is any effect on inflammatory blood markers (the level of a certain marker in the blood that is associated with inflammation; redness and swelling).
• Newly diagnosed patients with stages III-IV ovarian or endometrial cancer
• Receiving first-line carboplatin and paclitaxel chemotherapy after surgery
• ≥18 years, children under the age of 18 will be excluded due to rarity of disease
• Physician's clearance to participate in moderate-vigorous intensity exercise
• Able to read, write, and understand English
• Ability to understand and the willingness to sign an informed consent document
• Willing to undergo two venous blood draws for the study