a SIngle Center Study of Post-operative STEReotactic RAdiotherapY for Endometrial Cancer (SISTER-RAY)
Status: Recruiting
Location: See all (2) locations...
Intervention Type: Radiation
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The primary endpoint of the present prospective study is to assess the outcomes in terms of acute toxicity of post-operative stereotactic radiotherapy for endometrial cancer
Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: f
View:
• Age 18-80 years
• ECOG PS ≤ 2 or KPS ≥ 70%
• Patients diagnosed with endometrial cancer (endometrioid, serous cell, clear cell, carcinosarcoma) FIGO stage IB-IIIC1 candidate to post-operative external beam radiotherapy, based on molecular and histological findings
• Indications for chemotherapy and/or brachytherapy are not exclusion criteria for the purpose of the study
• Written Informed Consent
Locations
Other Locations
Italy
ARNAS Civico Hospital
NOT_YET_RECRUITING
Palermo
ARNAS Civico Hospital
RECRUITING
Palermo
Contact Information
Primary
FRANCESCO CUCCIA, MD
francesco.cuccia@arnascivico.it
+393334393336
Backup
GIUSEPPE FERRERA, MD
giuseppe.ferrera@arnascivico.it
+393471533715
Time Frame
Start Date: 2025-05-02
Estimated Completion Date: 2027-05
Participants
Target number of participants: 60
Treatments
Experimental: Experimental arm
Patients with endometrial cancer (stage IB-IIIC1) with histological and molecular features that require adjuvant external beam radiotherapy alone or in combination with chemotherapy and/or brachytherapy. Adjuvant radiotherapy will be performed with stereotactic body radiotherapy schedule of 30 Gy in 5 sessions.
Related Therapeutic Areas
Sponsors
Collaborators: Accuray Incorporated
Leads: ARNAS Civico Di Cristina Benfratelli Hospital