Comparison of Two-Point and Four-Point Cervical Injection Techniques Using Methylene Blue for Sentinel Lymph Node Mapping in Endometrial Cancer
Status: Recruiting
Location: See all (2) locations...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This clinical trial evaluates lymph node mapping in newly diagnosed endometrial cancer patients undergoing surgery. The standard technique uses a 2-point methylene blue cervical injection. The study aims to determine if increasing injection points improves mapping success.
Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Maximum Age: 75
Healthy Volunteers: f
View:
• Individuals diagnosed with stage I endometrial cancer based on CT and PET-CT imaging.
• Individuals with a pathologically confirmed diagnosis of stage I endometrial cancer.
Locations
Other Locations
Turkey
Ankara University
RECRUITING
Ankara
Dokuz Eylul University
RECRUITING
Izmir
Contact Information
Primary
Ibrahim Yalcin, MD
ibrahimyalcin73@gmail.com
+90 505 265 60 24
Backup
Ali Hakan Kula, MD
hkula95@gmail.com
+905358230685
Time Frame
Start Date: 2025-05-01
Estimated Completion Date: 2026-11-01
Participants
Target number of participants: 100
Treatments
Experimental: 2- Point Methylene Blue Injection
In the 2-point injection arm, participants will receive the standard sentinel lymph node (SLN) mapping technique using methylene blue. The procedure involves injecting methylene blue dye into two specific locations on the cervix:~At the 3 o'clock position At the 9 o'clock position
Active_comparator: 4- Point Methylene Blue Injection
In the 4-point injection arm, participants will receive the standard sentinel lymph node (SLN) mapping technique using methylene blue. The procedure involves injecting methylene blue dye into two specific locations on the cervix:~At the 2 o'clock position At the 4 o'clock position At the 8 o'clock position At the 10 o'clock position
Related Therapeutic Areas
Sponsors
Leads: Dokuz Eylul University