Erectile Dysfunction (ED) Clinical Trials

Find Erectile Dysfunction (ED) Clinical Trials Near You

Intérêt de la rééducation érectile précoce Par Sildénafil après radiothérapie et Proctectomie Pour Cancer du Rectum : Essai contrôlé randomisé

Status: Recruiting
Location: See all (14) locations...
Intervention Type: Drug, Other
Study Type: Interventional
Study Phase: Phase 3
SUMMARY

This study aims to evaluate the efficacy of erectile rehabilitation with Sildenafil, in men treated with neoadjuvant proctectomy and radiotherapy for rectal cancer, in preventing long-term erectile dysfunction at 12 months post-operatively.

Eligibility
Participation Requirements
Sex: Male
Minimum Age: 18
Maximum Age: 70
Healthy Volunteers: f
View:

• Men aged 18 to 70

• Patients undergoing surgery for cancer of the lower or middle rectum by total removal of the mesorectum with colorectal or coloanal anastomosis after neoadjuvant radiotherapy, with normal preoperative erectile function (defined by a combined IIEF erectile function domain score of at least 22).

• Nerve-conserving surgery

• Sexually active patient without treatment for erectile function prior to surgery

• Presence of a regular sexual partner (male or female)

• Adult having read and understood the information letter and signed the consent form

• Membership of a social security scheme

Locations
Other Locations
France
Chu Amiens
RECRUITING
Amiens
Hopital Beauvais
RECRUITING
Beauvais
Chu Besancon
RECRUITING
Besançon
Aphp Bicetre
RECRUITING
Bicêtre
Chu Bordeaux
RECRUITING
Bordeaux
Institut Bordeaux Colorectal
RECRUITING
Bordeaux
Chu Clermont-Ferrand
RECRUITING
Clermont-ferrand
Chu Lille
RECRUITING
Lille
Institut Paoli-Calmettes
RECRUITING
Marseille
Institut Du Cancer Montpellier
RECRUITING
Montpellier
Aphp Hegp
RECRUITING
Paris
Aphp St Antoine
RECRUITING
Paris
Chu Rouen
RECRUITING
Rouen
Chu Tours
RECRUITING
Tours
Contact Information
Primary
Valérie Bridoux
valerie.bridoux@chu-rouen.fr
0232881347
Backup
Julie Rondeaux, PhD
julie.rondeaux@chu-rouen.fr
0232885427
Time Frame
Start Date: 2025-09-25
Estimated Completion Date: 2030-02
Participants
Target number of participants: 188
Treatments
Active_comparator: Arm I (Sildénafil)
Sildénafil during 10 months (50mg daily), start 30 days after surgery
Placebo_comparator: Arm II (Placebo)
Patients receive placebo during 10 month (1 platelet per day)
Sponsors
Leads: University Hospital, Rouen

This content was sourced from clinicaltrials.gov