Erectile Dysfunction (ED) Clinical Trials

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Prospective Cohort Study of Somatic-Autonomic Nerve Grafting Technique to Restore Erectile Function in Patients With Persistent Erectile Dysfunction Post Radical Prostatectomy

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

A single arm prospective pilot trial evaluating the 1-year erectile recovery outcomes and the safety of patients undergoing a somatic to autonomic nerve grafting procedure for restoration of erectile function in patients who have lost erectile function following radical prostatectomy for prostate cancer. During this study a total of 100 patients who have persistent erectile dysfunction for more than 18 months post prostatectomy will undergo a post radical prostatectomy nerve restoration procedure (PRP-NR).

Eligibility
Participation Requirements
Sex: Male
Minimum Age: 18
Healthy Volunteers: f
View:

• Patients with persistent post prostatectomy erectile dysfunction as defined below:

‣ Severe ED (IIEF score 5-7) and more than 12 months from prostatectomy OR

⁃ Moderate ED (IIEF score 8-11) and more than 18 months from prostatectomy

• Patients must have had good pre-prostatectomy erectile function with a baseline IIEF score of ≥17 on self-reported assessment of historic function.

Locations
Other Locations
Canada
Jewish General Hospital
RECRUITING
Montreal
Contact Information
Primary
Victor McPherson, MD
victor.mcpherson@mcgill.ca
514-340-8222
Time Frame
Start Date: 2026-01-30
Estimated Completion Date: 2028-12
Participants
Target number of participants: 100
Treatments
Experimental: Post radical prostatectomy nerve restoration procedure
A somatic to autonomic nerve grafting procedure which will use a nerve graft of ilioinguinal nerve harvested from the inguinal canal to perform a bilateral end to side junction between the dorsal penile nerve and the penile corpora cavernosa
Sponsors
Leads: Sir Mortimer B. Davis - Jewish General Hospital
Collaborators: McGill University Health Centre/Research Institute of the McGill University Health Centre, Western University, Canada, Fox Chase Cancer Center

This content was sourced from clinicaltrials.gov