Esophageal Cancer Clinical Trials

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Definitive Radiotherapy for Cervical and Upper Thoracic Esophageal Cancer (ChC&UES): A Multi-center Real World Study

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

Cervical and upper thoracic esophageal cancer (ESCA) presents treatment challenges due to limited clinical evidence. This multi-center study (ChC\&UES) explores radical radio(chemo)therapy efficacy and safety

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Age 18 and older.

• Confirmation of esophageal cancer through histopathology or cytology.

• Primary tumor location within the cervical or upper thoracic segment, extending from the upper esophageal sphincter to the azygos vein.

• Absence of distant metastasis.

• Patients unable or unwilling to undergo surgical treatment for various reasons.

• Receipt of radical radiotherapy as the first-line treatment, with or without chemotherapy, immunotherapy, or targeted therapy.

• Undergoing conventional radiation therapy (1.8-2.0Gy per session, once per day).

• Receiving 3DCRT or IMRT radiotherapy.

• Availability of complete radiotherapy prescription dose information and follow-up records.

Locations
Other Locations
China
Because this study is a response to real-world patient treatment and outcomes
RECRUITING
Shijiazhuang
Contact Information
Primary
Wenbin Shen
wbshen2024@hebmu.edu.cn
+86 15831183879
Time Frame
Start Date: 2000-01-01
Estimated Completion Date: 2024-12-01
Participants
Target number of participants: 2600
Treatments
High dose radiotherapy (≥60Gy)
Patients who received 60 Gy or more than 60Gy radiation dose for radical radiation therapy for the primary tumor.
Low dose radiotherapy (50-<60Gy)
Patients who received 50-\<60Gy radiation dose for radical radiation therapy for the primary tumor.
Related Therapeutic Areas
Sponsors
Leads: Hebei Medical University Fourth Hospital
Collaborators: Shandong Cancer Hospital and Institute, Fudan University, Fujian Cancer Hospital, Tianjin Medical University Cancer Institute and Hospital, Cancer Institute and Hospital, Chinese Academy of Medical Sciences

This content was sourced from clinicaltrials.gov