A Comparison of Short-term and Long- Term Outcomes Between Ivor-Lewis and McKeown Minimally Invasive Esophagectomy

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Surgery is still the main treatment for esophageal cancer, however, the complication and mortality rate of open esophagectomy is high. As a result, the thoracoscopic- laparoscopic minimally invasive esophagectomy (MIE) was developed. The MIE mainly comprised two surgical approaches: MIE McKeown approach (cervical anastomosis) and MIE Ivor-Lewis approach (intrathoracicanastomosis). The MIE with intrathoracic anastomosis (Ivor-Lewis) is increasingly used for the treatment of mid and lower esophageal cancers. Our study is trying to compare the safety, feasibility, and short-term and long- term outcomes between MIE Ivor-Lewis approach and MIE McKeown approach for the treatment of lower thoracic esophageal cancer and esophageal- gastric junction.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 30
Maximum Age: 80
Healthy Volunteers: f
View:

• (I) Patients with clinically staged T1-3N0-2M0 tumors; good cardiopulmonary function;

• (II) Patients with lower thoracic esophageal tumors and esophageal- gastric junction tumor;

• (III) Patients without a previous history of cancer;

• (IV) Patients without a previous history of neck or chest surgery;

Locations
Other Locations
China
Yunpeng Zhao
RECRUITING
Jinan
Time Frame
Start Date: 2020-01-01
Estimated Completion Date: 2028-12-31
Participants
Target number of participants: 200
Treatments
Experimental: Ivor-Lewis group
minimally invasive esophagectomy (MIE) with intrathoracic anastomosis
Active_comparator: McKeown group
minimally invasive esophagectomy (MIE) with cervical anastomosis
Related Therapeutic Areas
Sponsors
Leads: The Second Hospital of Shandong University

This content was sourced from clinicaltrials.gov