• Patients with resectable cervical esophageal squamous cell carcinoma (cT1b-T4aN0-3M0);

• Cervical esophageal cancers spreads upwards to involve the hypopharynx and downwards to involve the thoracic esophagus can also be included;

• Aged 18-75 years;

• Without any contraindication of operation;

• Hemoglobin \>=90 g/L; Leukocytes \>=4.0x10\^9/L; Absolute neutrophil count \>=1.5x10\^9/L; Platelet \>=100x10\^9/L;Total bilirubin \<=1.5 ULN; ALT \<=2.5 ULN; AST \<=2.5 ULN; Serum creatinine \<=1.5 ULN or creatinine clearance rate \>=50 mL/min (Cocheroft-Gault);INR \<=1.5 ULN; APTT \<=1.5 ULN;

• Without other malignancies;

• Expected R0 resection;

• ECOG PS 0-1;

• Volunteered to participate in the study, signed the informed consent form.