Retrospective Review of Esophageal Cancer at MSKCC
Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Observational
SUMMARY
Residual tumor at the proximal or distal margin after esophagectomy is a known prognostic factor for poor survival outcomes in patients with esophageal cancer; however, the significance of the circumferential resection margin (CRM) remains controversial. In this study, the investigators sought to evaluate the prognostic significance of the CRM in patients with esophageal cancer undergoing resection.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Histologically confirmed esophageal adenocarcinoma (EAC) or esophageal squamous cell carcinoma (ESCC) undergoing esophagectomy
• Pathologic staged T3 tumors (pT3)
Locations
United States
New York
Memorial Sloan Kettering Cancer Center (All Protocol Activities)
RECRUITING
New York
Contact Information
Primary
Daniela Molena, MD
molenad@mskcc.org
212-639-3870
Backup
James Isbell, MD
isbellj@mskcc.org
212-639-6247
Time Frame
Start Date: 2016-12-13
Estimated Completion Date: 2026-02
Participants
Target number of participants: 4000
Treatments
Circumferential resection margin (CRM)
Participants will have a diagnosis of esophageal carcinoma and residual tumor \>1 mm from the CRM
Circumferential resection margin (CRM)-close
Participants will have a diagnosis of esophageal carcinoma and residual tumor \>0-1 mm from the CRM
Circumferential resection margin (CRM)+
Participants will have a diagnosis of esophageal carcinoma and residual tumor at the surgical CRM
Related Therapeutic Areas
Sponsors
Leads: Memorial Sloan Kettering Cancer Center