Prediction of Anastomotic Complications and Recurrent Laryngeal Nerve Injury Based on Postoperative Early Endoscopic Evaluation: a Prospective, Observational, Non-interventional Study

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Observational
SUMMARY

Analyze the correlation between the conformity of the anatomy (based on endoscopic examination) and postoperative anastomotic fistula and anastomotic stenosis; establish an anastomotic classification; and construct a predictive model combined with perioperative-related test indicators to provide more accurate risk assessment for clinical practice. Analyze the natural recovery process of postoperative recurrent laryngeal nerve injury in esophageal cancer by tracking vocal cord movement (based on endoscopic examination) and hoarseness symptoms; combined with perioperative related surgical and laboratory indicators, identify the relevant risk factors associated with delayed recovery of recurrent laryngeal nerve injury.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
View:

• Diagnosed with esophageal squamous cell carcinoma;

• 18 - 80 years old;

• ECOG PS 0-1;

• Thoracic esophageal cancer (20-40cm from the incisors);

• Received radical resection of esophageal cancer in our hospital from April 2024 to July 2024;

• Received the McKeown procedure in our hospital's single treatment group;

• Received gastric reconstruction and cervical anastomosis with a side-to-side anastomotic device;

• Complete clinical materials.

Locations
Other Locations
China
Shanghai Chest Hospital, Shanghai Jiao Tong University
RECRUITING
Shanghai
Time Frame
Start Date: 2024-04-01
Estimated Completion Date: 2025-12-31
Participants
Target number of participants: 250
Related Therapeutic Areas
Sponsors
Leads: Shanghai Chest Hospital

This content was sourced from clinicaltrials.gov