Multicenter Cohort Study of Chemo-radiotherapy After Endoscopic Submucosal Dissection for High-risk Early-stage Esophageal Cancer
Status: Recruiting
Location: See all (2) locations...
Intervention Type: Radiation
Study Type: Observational
SUMMARY
This multicenter, prospective observational cohort study has the potential to optimize individualized chemoradiotherapy regimen for early-stage esophageal cancer patients who have received endoscopic submucosal dissection.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 75
Healthy Volunteers: f
View:
• 1\. Esophageal cancer patients who are pathologically confirmed as pT1a-MM stage or pT1b stage after endoscopic submucosal dissection； 2. No definite contraindications for chemo-radiotherapy； 3. Informed consent has been signed； 4. Refused surgery after endoscopic submucosal dissection.
Locations
Other Locations
China
The Second Affiliated Hospital of Zhejiang University School of Medicine
RECRUITING
Hangzhou
The Second Affiliated Hospital of Zhejiang University, School of Medicine
NOT_YET_RECRUITING
Hangzhou
Contact Information
Primary
Jing Xu, MD
jing_xu@zju.edu.cn
0086-0571-87783521
Backup
Qichun Wei, PHD
qichun_wei@zju.edu.cn
0086-0571-87783521
Time Frame
Start Date: 2024-05-01
Estimated Completion Date: 2029-01-31
Participants
Target number of participants: 120
Treatments
Prophylactic chemoradiotherapy
pT1a -MM and pT1b-SM1 without pathological risk factors
Intensive chemoradiotherapy
pT1b-SM2; pT1a -MM and pT1b-SM1 with pathological risk factors
Radical chemoradiotherapy
Positive vertical margin or unknown margin
Related Therapeutic Areas
Sponsors
Leads: Second Affiliated Hospital, School of Medicine, Zhejiang University