Impact of Prehabilitation in Oncology Via Exercise- Esophageal

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this study is to determine the feasibility of a prehabilitation exercise and nutrition program (exercise and nutrition before a medical treatment) in adults with esophageal cancer before surgery (esophagectomy). The pre-surgery exercise and nutrition program will include resistance and aerobic training and nutrition supplementation during the weeks before surgery. We will also assess pre-surgical care needs in adults with esophageal cancer. Researchers will compare the exercise and nutrition intervention to usual care- which is standard medical care and post-surgery surveillance/follow-up to understand the impact of exercise and nutrition before surgery. We will follow-up with participants before surgery, and after surgery at 2 weeks, 6 weeks, and 4-months at appointments that coincide with clinical follow-ups. The main questions of this trials are: * Is exercise and nutrition supplementation before surgery for esophageal cancer feasible and acceptable to patients? * How does exercise and nutrition supplementation before surgery change physical function and psychosocial health? * What are important pre-surgical needs for adults with esophageal cancer?

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Men and women, age ≥ 18 years old

• Diagnosed with esophageal cancer

• Identified as esophagectomy surgery candidates at Hillman Cancer Center or UPMC Shadyside

• ≥ 2 weeks until scheduled esophagectomy

• Currently completing, or completed Neoadjuvant chemotherapy

• ECOG Performance Status Scale score of ≤ 2

• Ability to provide written informed consent

• Ability to understand, speak, and read English.

Locations
United States
Pennsylvania
UPMC Hillman Cancer Center
RECRUITING
Pittsburgh
Contact Information
Primary
Cara Battistella, MA
battistellac@upmc.edu
412-353-9102
Time Frame
Start Date: 2025-07-16
Estimated Completion Date: 2026-10-01
Participants
Target number of participants: 20
Treatments
Experimental: Home-based prehabilitation exercise and nutrition (PRE)
Interventions will include:~* Up to 8 weeks of 3-5 times per week resistance training and 3-5 times per week of aerobic training.~* IMPACT Advanced Recovery nutrition supplement drinks: 2 per day for 5 consecutive days leading up to surgery.
Active_comparator: Usual Care (CONT)
The CONT group will not receive any intervention during study participation and undergo usual medical treatment and surveillance during the duration of the study.
Related Therapeutic Areas
Sponsors
Leads: University of Pittsburgh

This content was sourced from clinicaltrials.gov