Fyza Y. Shaikh
Experienced in Esophageal Cancer
Experienced in Esophageal Cancer

Overview

Fyza Shaikh is an Assistant Professor in Cancer Immunology in the Department of Oncology in the Sidney Kimmel Comprehensive Cancer Center. She joined the faculty after completing her fellowship in medical oncology at Johns Hopkins School of Medicine (JHSOM) and residency in internal medicine at the University of Pittsburgh Medical Center as part of the ABIM research pathway. She received her MD and PhD in Microbiology and Immunology at Vanderbilt University School of Medicine. The Shaikh lab at JHSOM is focused on how the microbiome impacts host immunological responses to tumorigenesis and anti-tumor responses to immunomodulatory agents. The lab uses a combination of translational approaches using samples collected from human cohort studies and clinical trials as well as murine models to ask more detailed mechanistic questions and works across multiple tumor types (melanoma, lung, esophageal, head and neck, etc). The overall approach uses combination of clinical, computational, and lab-based techniques using a rich biorepository containing clinically annotated metadata with known and putative biomarkers of ICI response, such as PD-L1 and tumor mutational burden, paired with longitudinal fecal and plasma samples that correlate with clinical milestones (i.e. response/nonresponse by imaging and treatment-related toxicity). The goal is to focus on microbial functionality and build defined bacterial consortia that can then be tested in murine models to define colonization, metabolomics, and intra-tumoral immune response. This translational approach, with cross-sectional and longitudinal analysis of human samples, paired with mechanistic studies in murine models, has the potential to address both limitations in previously published studies and generate new hypotheses to make advances in this field and improve ICI responses for patients with advanced malignancies.

Dr. Shaikh is rated as an Experienced provider by MediFind in the treatment of Esophageal Cancer. Her top areas of expertise are Lung Cancer, Non-Small Cell Lung Cancer (NSCLC), Melanoma, and Esophageal Cancer.

Her clinical research consists of co-authoring 17 peer reviewed articles. MediFind looks at clinical research from the past 15 years. In particular, she has co-authored 1 article in the study of Esophageal Cancer.

Graduate Institution
Vanderbilt University School Of Medicine, Microbiology And Immunology, PhD, 2012
Residency
UPMC-University of Pittsburgh Medical Center, Internal Medicine, 2016
Specialties
Oncology
Licenses
Internal Medicine in MD
Board Certifications
American Board Of Internal Medicine
Fellowships
Johns Hopkins University School of Medicine, Oncology, 2020
Hospital Affiliations
The Johns Hopkins Hospital
Languages Spoken
English
Urdu
Gender
Female

Insurance

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Accepted insurance plans:

Aetna
  • EPO
  • HMO
  • POS
  • PPO
Capital Blue Cross
  • INSURANCE PLAN
  • MANAGED MEDICAID PLAN
  • MEDICARE MAPD
  • OTHER MEDICARE PART D
  • PPO
CareFirst
  • HMO
  • POS
  • PPO
Cigna
  • EPO
  • HMO
  • PPO
First Health
  • INSURANCE PLAN
  • MEDICARE PDP
  • PPO
Geisinger
  • HMO
  • POS
  • PPO
Humana
  • HMO
  • INDEMNITY
  • POS
  • PPO
Johns Hopkins Healthcare
  • HMO
  • MANAGED MEDICAID PLAN
  • MEDICARE MAPD
  • MEDICARE-MEDICAID PLAN
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Locations

The Johns Hopkins Hospital
Baltimore, MD 21287

Clinical Research

Clinical research consists of overseeing clinical studies of patients undergoing new treatments and therapies, and publishing articles in peer reviewed medical journals. Providers who actively participate in clinical research are generally at the forefront of the fields and aware of the most up-to-date advances in treatments for their patients.


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Areas of Expertise

MediFind evaluates expertise by pulling from factors such as number of articles a doctor has published in medical journals, participation in clinical trials, speaking at industry conferences, prescribing and referral patterns, and strength of connections with other experts in their field.

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