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Virological Surveillance of Acute Respiratory Infection in Primary Health Care in Metropolitan France

Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test
Study Type: Observational
SUMMARY

Every year in the fall and winter, numerous respiratory viruses (such as influenza viruses, SARS-CoV-2 (COVID-19), RSV, rhinovirus, and metapneumovirus) circulate in mainland France, causing acute respiratory infections (ARIs). These viruses can cause epidemics of varying severity, requiring close monitoring to determine their circulation levels and adapt public health measures accordingly. In France, ARI surveillance relies on two networks: the Sentinelles network in primary care and the RENAL network in hospitals. The Sentinelles surveillance is conducted in collaboration with Santé publique France, the National Reference Center for Respiratory Infection Viruses (Institut Pasteur and Hospices Civils de Lyon), and the University of Corsica. As part of the virological surveillance of ARIs, Sentinelles physicians are asked to collect nasopharyngeal swabs or saliva samples from a sample of patients presenting with an ARI during their clinic visits. This surveillance makes it possible to identify respiratory viruses circulating in primary care (general practice and pediatrics), to describe confirmed cases for each of the circulating viruses, and to estimate the impact of each on general practice. This surveillance also allows for the evaluation of the effectiveness of vaccines against influenza and COVID-19.

Eligibility
Participation Requirements
Sex: All
Healthy Volunteers: f
View:

• be seen by a general practitioner or pediatrician participating in the Sentinelles surveillance program;

• between week 40 (late September-early October) and week 15 (mid-April) of each year

• have an acute respiratory infection (ARI) as defined below: Sudden onset of fever (or feeling of fever) and respiratory symptoms

• have given oral consent to participate in this monitoring or, in the case of minors, oral consent given by the child's legal guardian(s) present at the consultation

Locations
Other Locations
France
IPLESP - UMR S 1136, N° BC 2908, Faculté de médecine Sorbonne Université, site Saint Antoine, 27 rue Chaligny
RECRUITING
Paris
Contact Information
Primary
Thierry BLANCHON, MD, PhD
thierry.blanchon@iplesp.upmc.fr
+33664846662
Backup
Olivier STEICHEN, MD, PhD
olivier.steichen@aphp.fr
Time Frame
Start Date: 2026-05-14
Estimated Completion Date: 2031-05-14
Participants
Target number of participants: 25000
Treatments
Individuals with an ARI consulting a GP or a private pediatrician in mainland France
Related Therapeutic Areas
Sponsors
Leads: Institut National de la Santé Et de la Recherche Médicale, France

This content was sourced from clinicaltrials.gov