Impact of Blood Phobia on Fainting Susceptibility

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The primary purpose of this study is to characterize cardiovascular autonomic function to emotional stimuli (blood-injection-injury phobia \[needle phobia\]) during an orthostatic (upright) challenge in individuals with and without known needle phobia. It is well established that emotional stress can produce hypotensive (low blood pressure) reactions. Interestingly, these hypotensive reactions to venipuncture (even with minimal blood drawn), insulin injections, finger sticks for blood sugar monitoring, dental care, and vaccinations can affect up to a quarter of adults and appear to be uniquely associated with blood-injection-injury phobia rather than other phobias. These hypotensive reactions can ultimately lead to a vasovagal syncope (fainting) response, and lead to increased avoidance of medical and dental procedures as a result of this phobia. Ultimately, this has severe implications on public health and places additional strain on the Canadian healthcare system. Currently, there is limited understanding surrounding the initiation of this response. Additionally, a comprehensive profile of cardiovascular autonomic function during exposure to provoking stimuli during orthostatic stress has not been captured in the literature. We will test individuals with and without blood-injection-injury phobia using our standard approach while exposing them to emotional stimuli.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 50
Healthy Volunteers: t
View:

• male and female

• 18 to 50 years old

• those without a suspected BII fear and those with a suspected fear

• english speaking

Locations
Other Locations
Canada
Simon Fraser University
RECRUITING
Burnaby
Contact Information
Primary
Victoria E Claydon, PhD
victoria_claydon@sfu.ca
7787828513
Backup
Vera E Lucci, PhD
vlucci@sfu.ca
7787828560
Time Frame
Start Date: 2024-03-30
Estimated Completion Date: 2026-12
Participants
Target number of participants: 20
Treatments
Experimental: Image and video data set shown with BII stimuli.
Participants will undergo this test on two separate days. On each day, participants will be asked to watch a series of videos and images. For this arm of the study, participants will view the BII phobia-related stimuli.
Placebo_comparator: Image and video data set shown with neutral stimuli.
Participants will undergo this test on two separate days. On each day, participants will be asked to watch a series of videos and images. For this arm of the study, participants will view the neutral stimuli.
Sponsors
Leads: Simon Fraser University

This content was sourced from clinicaltrials.gov