Internet-based Treatment for Patients Suffering From Severe Functional Somatic Disorders: A Randomized Controlled Trial.

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The aim of this multi-center, two-armed, randomized controlled trial is to assess the effect of a novel internet-based therapist-assisted treatment program One step at a time designed for the treatment of patients with moderate to severe functional somatic disorder (FSD). The trial will enroll 166 patients with FSD who will be randomized (1:1) to either the experimental condition (14 weeks' treatment with One step at a time) or the active control condition (GetStarted), which is a non-guided internet-based treatment program for patients with FSD. The trial will include patients aged 18-60 years with an established single/oligo-organ or multi-organ FSD diagnosis, with a duration of minimum 6 months. The primary outcome measures will be based on self-reported physical health (SF-36 PPH) and treatment satisfaction (CGI-I). The trial will be considered effective if a higher proportion of patients in the experimental condition report a clinically significant outcome compared with patients in the active control condition at the 3-month follow-up after treatment.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 60
Healthy Volunteers: f
View:

• Patients must fulfil the criteria for moderate-severe FSD operationalized as being diagnosed with either single/oligo-organ BDS, with 2 organ systems that are each affected by 3 or more symptoms, or multi-organ BDS, with 3 or 4 organ systems that are each affected by 3 or more symptoms.

• Patients must have symptom duration \> 6 months.

• If older than 25, patients must have been active in the labor market or educational system for at least 12 months during the last 2 years.

• Patient must have access to a computer or tablet with internet connection.

• Patient must be able to understand, read, and write Danish fluently.

Locations
Other Locations
Denmark
Department of Functional Disorders
RECRUITING
Aarhus C
Contact Information
Primary
Thomas T Lamm, MSc
THLAMM@rm.dk
61147069
Backup
Lisbeth Frostholm, Ph.D.
lisbeth.frostholm@aarhus.rm.dk
22618875
Time Frame
Start Date: 2022-08-24
Estimated Completion Date: 2026-10-31
Participants
Target number of participants: 166
Treatments
Experimental: Internet-delivered therapist-assisted treatment: One step at the time
One step at the times consists of 11 internet-delivered modules delivered over 14 weeks. Each module explores a different theme, primarily including elements from Cognitive Behavioral Therapy (CBT) for FSD, and includes FSD-related psychoeducation, various interactive exercises, and video and audio material. Interactions between patients and the therapist will take place via the telephone 3 times (start, mid-term, and end-of-treatment) and embedded messaging (therapist will respond to patients) approx. 2 times a week. The participating therapists are supervised every other week by specialized psychologists.
Active_comparator: Internet-delivered non-guided treatment: Get started
Get started is a non-guided self-help program, developed as an active control, that includes 4 modules consisting of FSD-related psychoeducation and guidance on making lifestyle improvements. Participants will have access to the Get started program for 14 weeks.
Sponsors
Leads: University of Aarhus
Collaborators: Sygehus Lillebaelt, Aarhus University Hospital

This content was sourced from clinicaltrials.gov

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