Revealing Protective Immunity to Influenza Using Systems Immunology
Status: Recruiting
Location: See location...
Intervention Type: Biological
Study Type: Interventional
Study Phase: Phase 4
SUMMARY
The goals of this study are to better understand the human immune response to influenza vaccines, specifically the live attenuated (weakened) influenza vaccine given as a nasal spray. Better understanding why this vaccine does not work as well in adults as it does in children may help design better influenza vaccines.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 49
Healthy Volunteers: t
View:
• Able to understand and give informed consent
• Participants of child bearing potential must agree to use effective birth control for the duration of the study. A negative urine pregnancy test must be documented prior to vaccination.
Locations
United States
Georgia
Hope Clinic of the Emory Vaccine Center
RECRUITING
Decatur
Contact Information
Primary
Daniel Graciaa, MD, MPH, MSc
dsgraci@emory.edu
404-712-1370
Backup
Daniel Graciaa, MD, MPH, MSc
404-712-9018
Time Frame
Start Date: 2024-10-14
Estimated Completion Date: 2027-02-28
Participants
Target number of participants: 50
Treatments
Experimental: Live Attenuated Influenza Vaccine
Participants receiving a single dose of the live attenuated influenza vaccine (LAIV).
Related Therapeutic Areas
Sponsors
Collaborators: Boston University
Leads: Emory University