Tracking Early Emergence of Sound Perception Impairments in FXS With Multimodal fNIRS/EEG- Infant

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Individuals with Fragile X Syndrome show differences in how they understand and learn language from infancy. They frequently have lifelong delays in speech and language as well. In addition, they experience other auditory symptoms, including being very sensitive to certain sounds as well as being more sensitive than others to loud sounds. The underlying brain activity for sound perception and speech learning in Fragile X is not well understood, especially in the infant and toddler years. This study uses behavioral assessment of speech and language abilities, neuroimaging, and hearing tests to understand how speech and hearing are different in children with Fragile X Syndrome.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 6 months
Maximum Age: 2
Healthy Volunteers: t
View:

• Diagnoses of Fragile X Syndrome, Typical Development, or History of Premature Birth

• able to sit independently

• English is spoken at home

Locations
United States
Ohio
Cincinnati Children's Hospital
RECRUITING
Cincinnati
Contact Information
Primary
Elizabeth Smith, PhD
elizabeth.smith3@cchmc.org
5135171383
Backup
Craig Erickson, MD
craig.erickson@cchmc.org
5136366553
Time Frame
Start Date: 2022-10-31
Estimated Completion Date: 2026-10-31
Participants
Target number of participants: 30
Treatments
Experimental: Speech Sounds
Participants listen to speech sounds while the investigators measure electrical and hemodynamic changes in the brain.
Related Therapeutic Areas
Sponsors
Leads: Children's Hospital Medical Center, Cincinnati

This content was sourced from clinicaltrials.gov

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