Circadian Rhythm and Other Individual Factors Among Memory Clinic Patients

Status: Recruiting
Location: See all (2) locations...
Intervention Type: Other
Study Type: Observational
SUMMARY

The CIRCAME study is a bicentric study of patients from 2 memory clinics in Paris. The main objective is to identify circadian rhythm components and other individual risk factors (sociodemographic, behavioral, and health related factors) associated with the diagnosis of subtypes (AD, Lewy bodies, vascular, frontotemporal dementia) and stages (cognitively healthy, mild cognitive impairment, clinical dementia) of dementia, independent of known risk factors (sociodemographic and genetic) and assess the relevance of use of these factors in primary care for screen of dementia including subtypes and stages. A secondary objective is to determine factors associated with progression of the disease, in terms of cognitive decline and limitations in activities of daily living, as well as progression to dementia among cognitively healthy controls and patients with mild cognitive impairment, up to 15 years after the inclusion period.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: t
View:

• Patient of legal age (18 or over)

• Signed informed consent form

• Patient affiliated to the french social security system

Locations
Other Locations
France
Centre de neurologie Cognitive / CMRR
RECRUITING
Paris
Hôpital de Jour Gériatrique et consultation mémoire
RECRUITING
Paris
Contact Information
Primary
Claire PAQUET, MDPhD
claire.paquet@aphp.fr
0140054313
Backup
Séverine SABIA, PhD
severine.sabia@inserm.fr
0157279046
Time Frame
Start Date: 2024-03-06
Estimated Completion Date: 2042-03
Participants
Target number of participants: 1500
Treatments
CIRCAME
This is the full cohort of patients that compose the CIRCAME study (N estimated = 1500)
CIRCAME-EYE ancillary study
Patients from CIRCAME seen at the Fernand-Widal hospital who will also undergo an eye examination (CIRCAME-EYE, N estimated = 1100, a sub-group of CIRCAME)
Sponsors
Collaborators: Institut National de la Santé Et de la Recherche Médicale, France, Fondation Rothschild Paris
Leads: Assistance Publique - Hôpitaux de Paris

This content was sourced from clinicaltrials.gov