Cholecystitis From a Microbiological and Histopathological Perspective
Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Observational
SUMMARY
The aim of this project is to investigate the presence of bacteria in the gallbladder wall and the bile in patients undergoing cholecystectomy, to determine if the standard empirical antibiotic treatment used currently is effective against the most common pathogens.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: t
View:
• Age above 18 years
• Signed consent form
• Patients having cholecystectomy performed at the Department of Surgery, Sygehus Lillebælt, Kolding.
Locations
Other Locations
Denmark
Sygehus Lillebælt
RECRUITING
Kolding
Contact Information
Primary
Malene B Dissing, MD
malene.borgager@rsyd.dk
004528745840
Backup
Louise L Pontoppidan, MD
louise.lerche.pontoppidan2@rsyd.dk
004527124689
Time Frame
Start Date: 2023-04-01
Estimated Completion Date: 2025-10
Participants
Target number of participants: 60
Treatments
Case group
Patients suffering from acute calculous cholecystitis undergoing subacute laparoscopic cholecystectomy.~Samples of bile and gallbladder wall specimens will be taken during surgery and will be sent for microbiological and pathological investigation
Control group
Patients suffering from painattacks due to gallstones, who have not symptoms of cholecystitis. The patients will undergo elective laparoscopic cholecystectomy.~Samples of bile and gallbladder wall specimens will be taken during surgery and will be sent for microbiological and pathological investigation
Related Therapeutic Areas
Sponsors
Leads: Organkirurgisk afdeling, sygehus lillebælt, Kolding