Effect of Esophageal Contractile Reserve on Changes in Esophageal Motility and Symptoms After Anti-reflux Surgery in Patients With Gastroesophageal Reflux Disease

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Observational
SUMMARY

rapid swallow (MRS) can assess the contractile reserve capacity of the oesophageal body and identify and diagnose oesophageal motility disorders, but the impact of preoperative oesophageal reserve capacity on postoperative symptoms and motility in patients with GERD remains unclear. The aim of this study was to assess the effect of pre-operative oesophageal reserve capacity on post-reflux symptoms and motility in patients with GERD by using a high-resolution oesophageal manometry-based provocation test, MRS, to track pre-operative ineffective oesophageal motility (IEM).

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Age over 18 years old

• Patients to be treated surgically for gastroesophageal reflux disease

• Ineffective esophageal motility diagnosed by high resolution esophageal manometry according to Chicago Classification version 4.0

• Obtaining Informed Consent

Locations
Other Locations
China
Department of Gastroenterology, Qilu Hospital, Shandong University
RECRUITING
Jinan
Contact Information
Primary
FeiXue Chen, MD
qlxhkqz@163.com
18560086108
Backup
Yanqing Li, phD
liyanqing@sdu.edu.cn
86-531-82169236
Time Frame
Start Date: 2022-04-22
Estimated Completion Date: 2026-06-01
Participants
Target number of participants: 70
Treatments
IEM in patients with GERD with normal MRS contraction
Esophageal motility determined by high resolution esophageal manometry and multiple rapid swallow (MRS) tests
IEM in patients with GERD with abnormal MRS contraction
Esophageal motility determined by high resolution esophageal manometry and multiple rapid swallow (MRS) tests
Sponsors
Leads: Shandong University

This content was sourced from clinicaltrials.gov