Gastroparesis Clinical Trials

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Acupuncture for POstoperative Gastric Emptying dElay (APOGEE): A Multicenter Randomized Controlled Trial

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This multicenter clinical trial, conducted at Qilu Hospital of Shandong University and collaborating institutions, prospectively assesses the efficacy and safety of acupuncture for postoperative delayed gastric emptying. Eligible participants will be prospectively enrolled and randomized into different groups per the study protocol. The primary endpoint is the reduction in the duration of delayed gastric emptying, while secondary endpoints include the complete resolution of cardinal gastroparetic symptoms, such as abdominal distension, nausea, and vomiting. All study procedures adhere to the ethical standards outlined in the approved protocol.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: f
View:

• Aged 18-80 years, regardless of sex.

• Patients who have undergone partial gastrectomy.

• Patients presenting with postoperative gastroparesis symptoms, confirmed by imaging or gastric emptying scintigraphy, and clinically diagnosed with gastroparesis.

• No severe cardiac, hepatic, renal, or coagulation dysfunction.

• No participation in other interventional clinical trials within the past month.

• Able to provide written informed consent and comply with the treatment and follow-up procedures.

Locations
Other Locations
China
Qilu hospital
RECRUITING
Jinan
Contact Information
Primary
zhibo Yan, PhD
201362006567@sdu.edu.cn
86+18560085166
Backup
wenbin Yu, PhD
wenbin_yu2003@163.com
86+18560085155
Time Frame
Start Date: 2026-04-01
Estimated Completion Date: 2028-06-01
Participants
Target number of participants: 176
Treatments
Experimental: Acupuncture Group
Acupuncture Group: Patients received acupuncture therapy in addition to the same standardized care regimen as provided to the control group.
Sham_comparator: Control Group
Control Group: Participants received standard care for postoperative gastroparesis, including dietary modification, gastrointestinal decompression, enteral nutritional support, and prokinetic agents, in combination with sham acupuncture.
Related Therapeutic Areas
Sponsors
Leads: Qilu Hospital of Shandong University
Collaborators: The People's Hospital of Yinan County, Weifang Yidu Central Hospital

This content was sourced from clinicaltrials.gov