The Use of Lidocaine Ophtesic Gel Versus Subconjunctival Xylocaine Injection in Pterygium Excision

Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 4
SUMMARY

In pterygium excision procedures, the subconjunctival injection of xylocain is regarded as an uncomfortable and painful step in the procedure. While already being studied in other ophthalmic procedures such as glaucoma surgery (7), application of topical lidocaine gel is likely to minimize pain. The gel has a longer surface contact time due to its consistency, providing not only a longer anesthetic effect, but protecting the corneal surface against desiccation, when compared to eye drops. The investigators hypothesize that Ophtesic 2% lidocaine gel is as effective as an anesthetic in pterygium excision as subconjunctival injection, while providing more comfort during surgery and less corneal dryness afterwards. Our goal is to compare both the anesthetic and corneal surface effect of topical 2% lidocaine gel to subconjunctival injection of xylocaine 2% solution with 0.125 epinephrine in pterygium surgery: * Compare the patients pain during and after surgery * Compare corneal dryness after surgery. * Evaluate possible secondary events

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 85
Healthy Volunteers: f
View:

• Indication of pterygium excision

Locations
Other Locations
Belgium
UZ Brussel
RECRUITING
Brussels
Contact Information
Primary
Lennert Hellinckx, Master
lennert.hellinckx@uzbrussel.be
0032 475397266
Time Frame
Start Date: 2023-09-01
Estimated Completion Date: 2024-12-31
Participants
Target number of participants: 50
Treatments
Experimental: Topical lidocaine gel
All patients will receive topical 2% lidocaine gel (Ophtesic lidocaine gel) prior to surgery
Active_comparator: Subconjunctival xylocaine injection
All patients will receive a subconjunctival injection with xylocaine 2% hydrochloride solution with 0.125 epinephrine will be injected with a 27-gauge needle
Sponsors
Leads: Vrije Universiteit Brussel

This content was sourced from clinicaltrials.gov

Similar Clinical Trials