The GRADE Randomized Trial: Glaucoma Rehabilitation With Action viDeo Games and Exercise

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Falls are one of the most serious public health concerns for seniors, with significant medical and economic consequences. This concern is even higher in patients with peripheral field loss due to glaucoma because of the patients' compromised visual input. The investigators' project proposes an innovative, entertaining, easily accessible and enjoyable intervention for improving mobility and postural control function in glaucoma patients with peripheral vision loss, who are more prone to falls and suffer from fear of falling. The new intervention examined in this project can be implemented in current vision and balance rehabilitation programs, and may benefit patients with different types of visual impairment to minimize their risk of falls and improve their quality of life.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 55
Maximum Age: 80
Healthy Volunteers: f
View:

• Presence of moderate to severe bilateral glaucomatous optic neuropathy (GON) from primary open-angle (including normal tension) or angle-closure glaucoma, as determined by an ophthalmologist, with abnormal Glaucoma Hemifield Test on standard Humphrey Field Analyzer 24-2 testing and matching nerve-fiber layer thinning on optical coherence tomography;

• Stable vision and visual field loss for at least 3 months;

• With a best-corrected distance acuity of 6/12 or better (equivalent to 0.3 logMAR acuity or better to confirm that participant's central vision is preserved);

• With a cognitive functional score of 22 or above in the Montreal Cognitive Assessment - Hong Kong version (to confirm participants' intact cognitive function).

Locations
Other Locations
Hong Kong Special Administrative Region
The Hong Kong Polytechnic University
RECRUITING
Hong Kong
Contact Information
Primary
Allen Cheong, PhD
allen.my.cheong@polyu.edu.hk
852-27666108
Backup
Mable Tong, BSc
mable.mp.tong@polyu.edu.hk
852-92523992
Time Frame
Start Date: 2023-09-09
Estimated Completion Date: 2025-12-30
Participants
Target number of participants: 56
Treatments
Active_comparator: Interactive action video-game training (AVG)
AVG using a Nintendo Switch gaming station will be administered in 20 sessions over 10 weeks (45 minutes per session, 2 sessions per week). Participants will be in standing position with game controllers or sensors attached to the body while playing games involving muscle stretching and strengthening exercises.
Experimental: Conventional physical training (PT)
Participants in the PT will receive 45-minutes conventional physical training.
Related Therapeutic Areas
Sponsors
Collaborators: The University of Hong Kong, University of Leicester, University of Waterloo
Leads: The Hong Kong Polytechnic University

This content was sourced from clinicaltrials.gov