Glaucoma Drainage Device and Endothelial Cell Loss Compare Trial
Status: Recruiting
Location: See all (8) locations...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
Glaucoma Drainage Device and Endothelial Cell Loss Compare Trial (DECLARE) is a multi-center, outcome-masked, randomized clinical trial. The purpose of this study is to compare glaucoma drainage device implantation in the anterior chamber (front part of the eye) and sulcus (small space between iris and front chamber of the eye) in efforts to minimize cell loss in the eye.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Medically uncontrolled glaucoma requiring GDD or GDD combined with phacoemulsification as the planned surgical procedure
• Candidate for GDD implantation for ciliary sulcus and AC tube
• Age greater than or equal to 18 years old
Locations
United States
California
University of California San Francisco
RECRUITING
San Francisco
Diablo Eye Associates
RECRUITING
Walnut Creek
Florida
Bascom Palmer Eye Institute
RECRUITING
Miami
Massachusetts
Massachusetts Eye and Ear
RECRUITING
Boston
Maryland
Wilmer Eye Institute, Johns Hopkins University
RECRUITING
Baltimore
North Carolina
University of North Carolina at Chapel Hill
RECRUITING
Chapel Hill
New York
University of Buffalo/State University of New York
RECRUITING
Buffalo
Other Locations
Canada
Prism Eye Institute, University of Toronto
RECRUITING
Toronto
Contact Information
Primary
Gui-shuang Ying, PhD
gsying@pennmedicine.upenn.edu
215-615-1514
Time Frame
Start Date: 2023-07-11
Estimated Completion Date: 2027-12
Participants
Target number of participants: 226
Treatments
Active_comparator: Sulcus tube placement
Glaucoma drainage device (GDD) implantation with tube placement in the ciliary sulcus
Active_comparator: Anterior chamber (AC) tube placement
Glaucoma drainage device (GDD) implantation with tube placement in the anterior chamber
Related Therapeutic Areas
Sponsors
Collaborators: Stanford University, National Eye Institute (NEI), University of California, San Francisco
Leads: University of Pennsylvania