Comparison of Phaco Surgery and Goniosynechialysis Versus Trabeculectomy Outcomes in Glaucoma Patients

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this clinical trial is to learn whether phacoemulsification combined with goniosynechialysis (Phaco-GSL) is as effective and safe as trabeculectomy in treating patients with primary angle-closure glaucoma. The main questions it aims to answer are: * Does Phaco-GSL provide similar or better intraocular pressure (IOP) control compared to trabeculectomy? * What are the rates of postoperative complications or adverse events between the two surgical approaches? * How do the two procedures compare in terms of visual acuity recovery and need for glaucoma medications? Researchers will compare Phaco-GSL to trabeculectomy to determine which procedure offers better overall outcomes for patients with angle-closure glaucoma. Participants will: Be randomly assigned to undergo either Phaco-GSL or trabeculectomy Attend scheduled follow-up visits at regular intervals (e.g., 1 week, 1 month, 3 months, 6 months, 12 months) for eye exams and pressure checks

Eligibility
Participation Requirements
Sex: All
Minimum Age: 40
Healthy Volunteers: f
View:

• Age ≥ 40 years

• Peripheral anterior synechiae (PAS) \>180°

• Glaucomatous optic neuropathy with visual field loss

• Intraocular pressure (IOP) \> 21 mmHg despite medication

• Ability to consent and comply with follow-up

• Cataract grade 1 to 3 according to LOCS III

• Best corrected visual acuity (BCVA) ≥ 0.3 logMAR (equivalent to 20/40 Snellen or worse)

Locations
Other Locations
Viet Nam
HCMC University of Medicine and Pharmacy
RECRUITING
Ho Chi Minh City
Contact Information
Primary
Hai Thanh Le, MSc
haileopto@gmail.com
+61 450390405
Time Frame
Start Date: 2025-06-01
Estimated Completion Date: 2027-09-10
Participants
Target number of participants: 82
Treatments
Active_comparator: standard trabeculectomy with 5FU
Experimental: Phacoemulsification with Goniosynechialysis
Sponsors
Leads: University of Medicine and Pharmacy at Ho Chi Minh City

This content was sourced from clinicaltrials.gov

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