oCular Examination at Cell RESolution With Optical TransmissionTomography

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Understanding the pathogenesis of eye diseases has benefited greatly from recent advances in ophthalmic imaging. However, current clinical imaging systems, such as optical coherence tomography (OCT), are limited in terms of resolution, acquisition speed or access to certain eye functions. Our team has participated in the development of a new generation of imaging technology known as optical transmission tomography (OTT), which enables imaging of the anterior parts of the eye with high cellular resolution, a wide field of view and reduced examination delay.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: t
View:

⁃ For Patients:

• 200 subjects aged 18 to 80 years;

• Male or female;

• with an ocular disease affecting the cornea, ocular surface, lens (cataract) or glaucoma, or requiring refractive surgery or post-refractive surgery follow-up;

• Are covered by the French Assurance Maladie;

• Have signed an express, free and informed consent form.

⁃ For Healthy volunteers:

• 100 subjects aged 18 to 80 years;

• Male or female;

• Healthy subjects with no known pathology directly or indirectly affecting ocular structures;

• Covered by the French Assurance Maladie.

• Having signed an express, free and informed consent form.

Locations
Other Locations
France
Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts
RECRUITING
Paris
Contact Information
Primary
Nabil BROUK
nbrouk@15-20.fr
00 33 1 40 02 11 44
Time Frame
Start Date: 2024-11-12
Estimated Completion Date: 2029-11-12
Participants
Target number of participants: 300
Treatments
Experimental: Patients with Ocular Disease
Patients: an imaging examination by each system (OTT + OCT + specular microscopy) will be carried out by two different operators, and several imaging images will be taken from different positions. These examinations will be performed at the inclusion visit and at follow-up visits as part of the usual management of the disease up to a maximum of 4 years
Active_comparator: Healthy volunteers
Healthy Volunteers: an imaging examination by each system (OTT + OCT + specular microscopy) will be carried out twice, at the inclusion visit and at 24 months (2 years), the maximum duration of participation for healthy volunteers. Several imaging sessions will be carried out by two different operators at different positions
Related Therapeutic Areas
Sponsors
Leads: Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts

This content was sourced from clinicaltrials.gov

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